Oklahoma Bioinformatics Society Symposium
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OKBIOS 2005

Plenary Speakers
Andrey Rzhetsky
Assistant Professor at the Department of Biomedical Informatics and the Genome Center, Columbia University
Andrey Rzhetsky received his training in Mathematical Biology in the heart of the West Siberia (Novosibirsk). He did his postdoctoral work with Professor Masatoshi Nei at Pennsylvania State University, developing models of nucleotide substitution and algorithms for phylogenetic tree inference. Currently, he is an Assistant Professor at the Department of Biomedical Informatics and the Genome Center at Columbia University in the New York City. His research is focused on computational analysis of signal-transduction pathways.
 
Bruce Roe
George Lynn Cross Research Professor of Chemistry and Biochemistry at The University of Oklahoma

Academic Training:
  • BA 1959-1963 Hope College, Holland, Michigan - Chemistry, Mathematics, Physics.
  • MA 1963-1967 Western Michigan University, Kalamazoo, Michigan - Chem., Biochem.
  • Ph.D. 1968-1970 Western Michigan University, Kalamazoo, Michigan - Chem., Biochem.

Professional Experience:

  • 1963-1968 Marshall Public Schools - High School Chemistry and Physics Teacher.
  • 1968-1970 Western Michigan University - Graduate Teaching Fellow
  • 1970-1973 SUNY at Stony Brook, N.I.H. Postdoctoral Research Fellow.
  • 1973-1977 Kent State University - Assistant Professor, Department of Chemistry.
  • 1977-1981 Kent State University - Associate Professor, Department of Chemistry and Research Associate Professor, Northeastern Ohio University College of Medicine, Department of Pathology and Biology.
  • 1979-1981 Case Western Reserve University - Adjunct Associate Professor, Department of Polymer Chemistry.
  • 1978-1979 Sabbatical Research Year in Dr. Frederick Sanger's Laboratory, Medical Research Council, Cambridge, England.
  • 1981-pres. Professor, Dept. Chemistry and Biochemistry, University of Oklahoma and Adjunct Professor, Dept. Biochem. and Molec. Biology, OU Health Sciences Center.
  • 1997-pres. George Lynn Cross Research Professor of Chemistry and Biochemistry University of Oklahoma

Honors and Professional Activities:

  • Dupont Scholarship, Hope College, 1962-1963
  • Todd Fellowship, Western Michigan University, 1969-1970.
  • NIH Postdoctoral Research Fellow, SUNY at Stony Brook, 1970-1973.
  • NIH Research Career Development Award, 1976-1981.
  • University of Oklahoma Regents' Award for Research, 1984.
  • NIH Biochemistry Study Section and Site Visit Team, 1982-1983.
  • Chairman of four NIH Special Study Sections, 1984-1988.
  • Member of twelve NIH and DOE Human Genome Special Study Sections, 1989-present.
  • Member of NLM Informatics Study Section, 1993-present
  • Oklahoma Health Research Act Committee Member, 1986-present.
  • Chairperson, OU Recombinant DNA Committee - 1989-present
  • NSF-EPSCORE Committee Established Investigator, 1985-1988.
  • MASUA Honor Lecturer, 1986-1987 academic year.
  • American Society for Biochemistry and Molecular Biology
  • American Association for the Advancement of Science
  • Journal Editorial Board Member - BioTechniques, GENE - Computing for Molecular Biology Information Service, Genome Research.
  • Editor of the BioTechniques DNA Sequencing Issue.
  • Journal Editor of Methods: DNA Sequencing Issue

Specialties by Training and Experience:

  • Human, Mouse, and Bacterial Genomic Sequencing
  • Automated methods for DNA sequence analysis, Recombinant DNA, cloning, and tumor specific gene nucleotide sequence analysis
  • In vitro and in vivo DNA replication, gene transcription and mRNA translation
  • Structure and function of tRNA in normal and abnormal mammalian tissues
  • Studies on the role of modified nucleotides in mammalian tRNA.
 
Christopher L. Greer
Program Director, Division of Biological Infrastructure, National Science Foundation

Dr. Greer received his PhD degree from the University of California, Berkeley where he worked with Dr. Randy Schekman on cytoskeleton structure and function. Postdoctoral training was undertaken with Dr. John Abelson at CalTech and focused on RNA splicing mechanisms. Dr. Greer was a member of the faculty at the University of California at Irvine in the Department of Biological Chemistry for approximately 18 years where his research on gene expression pathways was supported by grants from the NSF, NIH and the American Heart Association. During that time, he was founding Executive Officer of the RNA Society, an international professional organization with more than 800 members from 21 countries worldwide.

Dr. Greer has been a rotator and, more recently a member of the permanent staff at the National Science Foundation. He has served as Program Director and Acting Deputy Division Director in the Division of Molecular and Cellular Biosciences. His current appointment as Program Director in the Division of Biological Infrastructure includes responsibility for certain of the crosscutting activities in the Emerging Frontiers Division including Research Coordination Networks and Frontiers in Integrative Biological Research. Dr. Greer is currently serving as Executive Secretary of the Long-Lived Data Collections Task Force of the National Science Board.

 
Julio Collado-Vides
Professor of Computational Genomics, University of Cuernavaca

J.C. obtained his B.S. in 1981, M.Sc. in physical chemistry in 1985 and Ph.D. in 1989 at the National Autonomous University of Mexico. Then he spent 3 years in the Department of Biology at MIT working in a grammatical model of gene regulation in the laboratory of Dr. Boris Magasanik. Later on in 1992 he obtained the recognition as Fellow of the John Simon Guggenheim Foundation That year J.C. went to the Center of Nitrogen Fixation within the National Autonomous University of Mexico, in Cuernavaca City where he established the fist laboratory of bioinformatics in Mexico and is currently the Head of the Program of Computational Genomics. This laboratory has been recognized as the EMBNET Mexican node of bioinformatics. He was President Founder of the Mexican Society of Genomics (2000).

J.C. made the formal proof that gives support to a grammatical model of gene regulation in bacteria, developed such a model, which was implemented in a syntactic parser of regulatory elements for E.coli. Subsequently, he established the largest database in bacteria on transcriptional regulation and operon organization, RegulonDB, partly contained also in EcoCyc. His work is focused in implementing computational methods to predict promoters, regulatory sites, operons, as well as, more recently, methods to analyze microarray data.

He contributed to the annotation of regulation of the complete E.coli genome published in 1997 in Science, and has currently more than 50 papers in international peer-reviewed journals, (list of publications available at http://www.cifn.unam.mx/Computational_Genomics/publications-I-2000.html), cited more than 3500 times, as well as over 12 chapters in books. Additionally, he has edited two books in MIT Press, “Integrative Approaches to Molecular Biology eds. Collado-Vides J., Smith T. and Magasanik B. MIT Press (1996), and more recently “Gene Regulation and Metabolism: Post-Genomic Computational Approaches eds. Collado-Vides J. and Hofestadt R. MIT Press (2002).

Dr. Collado-Vides has organized two international conferences in Mexico, and co-organized three in Germany, an international workshop in bioinformatics, and participated in several Scientific and Organizing Committees of conferences in computational biology. He is currently the P.I. of the Mexican genome initiative –of the Rhizobium etli soil bacteria-, and his research has received grant support from UNAM and the Council of research in Mexico, as well as from DOE and NIH.

 
Thomas C. Kupiec, PH.D.
President and CEO of two companies Analytical Research Labs and DNA Solutions

Dr. Thomas Kupiec is President and Director of Laboratories of Analytical Research Laboratories. He received his Ph.D in Pharmaceutical Sciences from the College of Pharmacy University of Oklahoma Health Sciences Center in 1997. He also received a M.Ed in Chemistry Education and a B.S. in Chemistry from Central State University in Edmond, Oklahoma.

Dr. Kupiec has held many teaching appointments. He currently serves as part of the Graduate Faculty at the OU Health Sciences Center. He has taught classes in the area of Neurotoxicology and Pharmacogenomics at University of Oklahoma College of Pharmacy. He has taught forensic toxicology and various general chemistry classes as well. He has also served as an adjunct professor of chemistry at the University of Central Oklahoma, Rose State College, Oklahoma City Community College, and Oklahoma State University Tech Branch. Dr. Kupiec has published and presented approximately numerous articles and abstracts.

In addition to his academic pursuits, Dr. Kupiec has served in many professional capacities. At Analytical Research Laboratories, Dr. Kupiec is responsible for all technical areas and recruitment of new business in the pharmaceutical and forensic toxicology arenas. In this capacity, he has also mentored numerous students and technicians through the OCAST intern program and local Universities. Dr. Kupiec also serves as the President and CEO of DNA Solutions, Inc. Additionally, he presently offers consultation services and expert witness testimony in the field of forensic toxicology and pharmaceutical sciences. Dr. Kupiec has testified in over 100 cases in municipal, state and federal courts, involving both civil and criminal issues. Prior to these current appointments, Dr. Kupiec served as the Associate Director of the Workplace Drug Testing Division of NWT, Inc. Dr. Kupiec has also served as a Senior Research Chemist, Toxicology Section, for the Federal Aviation Administration (FAA) and the Civil Aeromedical Institute (CAMI). He has served as a Senior Forensic Chemist at the Oklahoma City Police Department in drug analysis as well.

Dr. Kupiec’s professional affiliations include membership in the American Academy of Forensic Sciences, American Association of Pharmaceutical Scientists, American Society of Heath System Pharmacists, the Society of Forensic Toxicologists, and Sigma Xi – The Scientific Research Society.

Dr. Kupiec has received numerous awards for his work. He has received the Federal Aviation Administration’s Superior Accomplishment Award. He has also received an Outstanding Young Men of America Award. The Oklahoma City Policy Department also awarded Dr. Kupiec a Certificate of Achievement.